How I can perform post layout simulation?
Wouldn't that depend on the tools you are using for simulation, how you are producing your netlist, and any scripts or automated configuration your employer may provide? I'm afraid that to answer usefully requires a lot more detail.
I'm just assuming you are using Pyxis (formerly IC Station) or Olympus, given you are posting to this group, but if you are here because of Calibre chances are it is some other layout tool.
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