In my project there are more then 200 passive components. I need to assign Reference Designator in sequence according to channel. Is it possible to change the reference designator through scrip ? instead of doing changing one by one ?
You can do this via several methods including scripting, see this community for scripting help Automation and Scripting
Depending on the complexity of what you are trying to do you may be able to achieve it using Find and Replace Text (Ctrl+H) to do a simple text substitution, or by using the Add Properties command (Edit - Add Properties) or using Tools - Renumber Reference Designators.
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